Snake Fungal Disease
What is it?
Snake fungal disease (ophidiomycosis) is caused by the fungus Ophidiomyces ophidiicola. It affects wild snakes across the eastern US, including Florida, and can occur in captive snakes. It causes skin lesions and can become severe.
What signs should I watch for?
Signs to watch for include crusty, thickened, or discolored scales; swelling of the face or around the eyes; frequent shedding; skin ulcers or nodules; and weight loss.
How is it diagnosed and treated?
Diagnosis uses swabs or biopsies for laboratory testing. Treatment includes antifungal therapy and supportive care, and improving husbandry.
Can it be prevented, and what's the outlook?
- Outcomes vary.
- Never house wild-caught snakes with pets, and quarantine new animals.
Reviewed by the Adler Veterinary Hospital veterinary team, October 2026.
Wild snakes in the eastern US, including Florida; captive snakes
Who's at risk:
Crusty scales, face swelling, frequent shedding, skin ulcers
Main signs:
Schedule a visit soon
Urgency:
When to call a vet right away
- Crusty or thickened scales, especially around the head
- Swelling of the face or around the eyes
- Skin ulcers or nodules
- Weight loss
- Breathing difficulty
Not sure whether it can wait? Call us anyway. Our team can help you decide.
Source:
Related conditions
Shedding Problems
Snake Mites
Thermal Burns