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Splenic Tumors (Including Hemangiosarcoma)

Painted illustration of a splenic tumor in a dog

What is it?

The spleen is a blood-filtering organ in the abdomen, and it is the most common site of vascular (blood-vessel) tumors in dogs. A hemangioma is benign, much like a large blood blister. A hemangiosarcoma is a cancer that can spread to other organs. Up to 70% of dogs with splenic tumors have hemangiosarcoma; the rest have a hemangioma or another tumor such as lymphoma. Large breeds such as German shepherds, Labrador retrievers, and golden retrievers are predisposed, but dogs of any size can be affected.

What signs should I watch for?

Splenic tumors may cause no signs until they rupture, which can happen without any injury. Bleeding into the abdomen causes lethargy, weakness, collapse, poor appetite, and a swollen belly. Severe untreated bleeding can be fatal.

How is it diagnosed and treated?

Abdominal ultrasound often finds the tumor. Removing the spleen (splenectomy) both treats the tumor and prevents further bleeding, and the tissue is sent to a pathologist to identify the tumor type. With hemangiosarcoma, tests such as bloodwork, urinalysis, clotting tests, X-rays, and ultrasound look for spread, and chemotherapy is usually recommended. If your dog has a known splenic mass, keep them quiet, watch for signs of bleeding, and avoid medicines that increase bleeding risk, such as NSAIDs, before surgery.

Can it be prevented, and what's the outlook?

  • There is no known way to prevent these tumors.
  • Hemangiomas have a good outlook once removed.
  • Hemangiosarcoma has a guarded to poor outlook because it often spreads and can bleed again elsewhere.
  • Once a splenic mass is found, it is best not to delay treatment.

Reviewed by the Adler Veterinary Hospital veterinary team, October 2026.

Large breeds such as German shepherds, Labradors and golden retrievers

Who's at risk:

Sudden weakness, collapse, pale gums, swollen belly

Main signs:

Emergency — see a vet now

Urgency:

When to call a vet right away

  • Sudden weakness or collapse
  • Lethargy with a swollen belly (signs of internal bleeding)

Not sure whether it can wait? Call us anyway. Our team can help you decide.

Source:

Related conditions

Immune-Mediated Hemolytic Anemia (IMHA)

IMHA

Bloat (Gastric Dilatation-Volvulus, GDV)

Bloat (GDV)

Liver Tumors

Liver Tumors

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