top of page

Mast Cell Tumors

Painted illustration of mast cell tumors in a dog

What is it?

Mast cell tumors are the most common skin cancer in dogs. They can look like almost any lump, from a small raised bump to a swollen, red mass, and may change size from day to day. Boxers, Boston terriers, Labradors, and pugs are among breeds at higher risk.

What signs should I watch for?

Signs to watch for include A new or changing skin lump; A lump that swells, reddens, or itches; and vomiting or appetite loss in some cases.

How is it diagnosed and treated?

A needle sample can usually identify the tumor; a biopsy determines its grade. Surgical removal with a margin of normal tissue is the main treatment. Higher-grade tumors may need further staging, radiation, or chemotherapy.

Can it be prevented, and what's the outlook?

  • Outlook depends heavily on grade and stage; many low-grade tumors are cured by surgery.
  • Have every new lump checked.

Reviewed by the Adler Veterinary Hospital veterinary team, October 2026.

Dogs; Boxers, Boston terriers, Labradors, pugs at higher risk

Who's at risk:

New or changing skin lump that swells, reddens, or itches

Main signs:

Schedule a visit soon

Urgency:

When to call a vet right away

  • A lump that suddenly swells, reddens or grows quickly
  • Vomiting or loss of appetite
  • Black, tarry stools
  • Lethargy
  • A rounded or swollen belly

Not sure whether it can wait? Call us anyway. Our team can help you decide.

Source:

Related conditions

Histiocytoma

Histiocytoma

Lipoma (Fatty Tumor)

Fatty Tumor (Lipoma)

Skin Cysts (Follicular Cysts)

Skin Cysts

Next steps

Watch a related video

Helpful products

Schedule an appointment

bottom of page