Upper Respiratory Infections

What is it?
Feline upper respiratory infections are like a bad cold, usually caused by feline herpesvirus or calicivirus, sometimes with bacteria involved. They spread easily in shelters and multi-cat homes. Kittens are most often affected.
What signs should I watch for?
Signs to watch for include sneezing and nasal discharge; runny, red, or squinting eyes; fever and decreased appetite; mouth ulcers (with calicivirus); and open-mouth breathing in severe cases.
How is it diagnosed and treated?
Diagnosis is usually based on signs; testing is sometimes done. Most cats recover at home with supportive care such as keeping the nose clean, encouraging eating, and eye or other medications when needed.
Can it be prevented, and what's the outlook?
- Core vaccines lessen severity.
- Many cats carry herpesvirus for life and may flare under stress.
- Seek care if your cat stops eating or breathing is difficult.
Reviewed by the Adler Veterinary Hospital veterinary team, October 2026.
Kittens, shelter and multi-cat homes
Who's at risk:
Sneezing, nasal discharge, sore eyes, fever, poor appetite
Main signs:
See a vet within a day or two
Urgency:
When to call a vet right away
- Not eating
- Difficulty breathing or open-mouth breathing
Not sure whether it can wait? Call us anyway. Our team can help you decide.
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