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Chronic Kidney Disease

Painted illustration of chronic kidney disease in a cat

What is it?

Chronic kidney disease (CKD) is a gradual loss of kidney function, very common in older cats. The kidneys have large reserves, so signs often appear only after most function is gone.

What signs should I watch for?

Signs to watch for include drinking and urinating more, weight loss and poor appetite, vomiting, poor coat and bad breath, and weakness or lethargy.

How is it diagnosed and treated?

Blood and urine tests, including newer early markers, confirm CKD and stage it; blood pressure checks are also important. Treatment aims to slow progression: kidney-friendly diets, hydration support, and managing problems like high blood pressure, nausea, or low potassium.

Can it be prevented, and what's the outlook?

  • CKD can't be reversed, but many cats live comfortably for years with care.
  • Senior blood and urine screening helps catch it early.

Reviewed by the Adler Veterinary Hospital veterinary team, October 2026.

Older cats

Who's at risk:

Drinking and urinating more, weight loss, poor appetite

Main signs:

Ongoing management with your vet

Urgency:

When to call a vet right away

  • Poor appetite or not eating
  • Vomiting or diarrhea
  • Lethargy or depression
  • Bad breath or mouth ulcers
  • Pale gums (a sign of anemia)
  • Signs that seem to start or worsen suddenly

Not sure whether it can wait? Call us anyway. Our team can help you decide.

Source:

Related conditions

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Pregnancy Nutrition

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Dental & Tooth Resorption

Lower Urinary Tract Disease and Urethral Obstruction

Urinary Blockage

Next steps

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